Persistent Edematous-plaque Photosensitivity Observed with Sitagliptin Phosphate (Januvia®)

Author

Sherea Stricklin
William V. Stoecker, Missouri University of Science and TechnologyFollow
Ryan K. Rader
Antoinette F. Hood
Jerome Z. Litt
Thomas P. Schuman, Missouri University of Science and TechnologyFollow

Abstract

Photosensitivity to sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, is reported. No previous reports of photosensitivity to any DPP-4 inhibitors are known. Physical examination of the patient revealed edematous plaques confined to sun-exposed areas of the skin. An unusual finding in this case was the spongy sensation upon palpation of the plaques. Histopathology revealed parakeratosis and abundant eosinophils, supporting the clinical impression of cutaneous drug sensitivity. The eruption finally cleared, approximately two years after onset. © 2012 Dermatology Online Journal.

Recommended Citation

S. Stricklin et al., "Persistent Edematous-plaque Photosensitivity Observed with Sitagliptin Phosphate (Januvia®)," Dermatology Online Journal, University of California, Davis, Jan 2012.

Department(s)

Chemistry

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2012 University of California, Davis, All rights reserved.

Publication Date

01 Jan 2012