Ecofriendly Method to Dissolve Chitosan in Plain Water
Chitosan is an important and abundant natural-based polymer, and it has broad applications. However, dissolving chitosan in plain water is a challenge, which mostly limits the biomedical applications of chitosan materials. Herein, we report an ecofriendly dissolution method to obtain a plain water-based chitosan solution for the first time. In this method, dissolving chitosan in ionic liquid followed by overnight freezing at -20 °C and subsequent solvent exchange with plain water at room temperature results in a stable chitosan dispersion in water with nanosize, namely water-based, chitosan pseudosolution. The overall process is ecofriendly. This new method augments the quality and processability of chitosan solutions used in manufacturing and bioprocessing and promotes the biomedical applications of chitosan-based products.
B. Li et al., "Ecofriendly Method to Dissolve Chitosan in Plain Water," ACS Biomaterials Science and Engineering, vol. 5, no. 12, pp. 6355-6360, American Chemical Society (ACS), Dec 2019.
The definitive version is available at https://doi.org/10.1021/acsbiomaterials.9b00695
Chemical and Biochemical Engineering
Keywords and Phrases
chitosan; dissolution method; ionic liquid; plain water-based solution; pseudosolution
International Standard Serial Number (ISSN)
Article - Journal
© 2019 American Chemical Society (ACS), All rights reserved.
09 Dec 2019