Dendrimers for Pharmaceutical and Biomedical Applications
Dendrimers are a unique class of synthetic macromolecules having a highly branched, three-dimensional, nanoscale architecture with very low polydispersity and high functionality. Structural advantages allow dendrimers to play an important role in the fields of nanotechnology, pharmaceutical and medicinal chemistry. This review discusses several aspects of dendrimers, including preparation, dendrimer-drug coupling chemistry, structural models of dendrimer-based drug delivery systems, and physicochemical and toxicological properties.
H. Yang and W. J. Kao, "Dendrimers for Pharmaceutical and Biomedical Applications," Journal of Biomaterials Science, Polymer Edition, vol. 17, no. 1, pp. 3-19, VSP, Jan 2006.
The definitive version is available at https://doi.org/10.1163/156856206774879171
Chemical and Biochemical Engineering
Keywords and Phrases
Biomaterials; Dendrimer; Drug delivery; Nanomedicine; Polyamidoamine (PAMAM) dendrimer
International Standard Serial Number (ISSN)
Article - Journal
© 2006 VSP, All rights reserved.
01 Jan 2006