Title

Dendrimers for Ocular Drug Delivery

Abstract

Existing methods of administering ocular drugs are limited in either their safety or efficiency. Nanomedicine therapies have the potential to address this deficiency by creating vehicles that can control drug biodistribution. Dendrimers are synthetic polymeric nanoparticles with a unique, highly organized branching structure. In recent years, promising results using dendrimer vehicles to deliver ocular drugs through different routes of administration have been reported. In this minireview, we briefly summarize these results with emphasis on the dendrimer modifications used to target different ocular structures.

Department(s)

Chemical and Biochemical Engineering

Comments

This work was supported by the National Institutes of Health (R01EY024072).

Keywords and Phrases

Dendrimer; Nanomedicine; Ocular drug delivery

International Standard Serial Number (ISSN)

0008-4042; 1480-3291

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2017 Canadian Science Publishing, All rights reserved.

Publication Date

11 May 2017

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