Zinc-based glass polyalkenoate cements have been synthesised and their potential use in orthopaedic applications investigated. Zinc ions were released from the materials in a rapid burst over the first 24 h after synthesis, with the release rate falling below detectable levels after 7 days. Cement-implanted bone samples were prepared, and the released zinc was shown, using energy dispersive X-ray analysis, to penetrate from the cement into the adjacent bone by up to 40 μm. Finally, the cements exhibited antibacterial activity against Streptococcus mutans and Actinomyces viscosus that reflected the pattern of zinc release, with the inhibition of growth greatest shortly after cement synthesis and little or no inhibition measureable after 30 days. © Springer Science + Business Media, LLC 2006.
D. Boyd et al., "The Antibacterial Effects of Zinc Ion Migration from Zinc-Based Glass Polyalkenoate Cements," Journal of Materials Science: Materials in Medicine, vol. 17, no. 6, pp. 489 - 494, Springer, Jun 2006.
The definitive version is available at https://doi.org/10.1007/s10856-006-8930-6
Chemical and Biochemical Engineering
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01 Jun 2006