Simultaneous Determination of Amino Acids in Urine by HPLC-MS/MS for Breast Cancer Risk Screening

Presenter Information

Alexandra Cristea

Department

Chemistry

Major

Chemistry

Research Advisor

Ma, Yinfa

Advisor's Department

Chemistry

Funding Source

OURE

Abstract

The use of biomarkers in the field of disease detection is a growing field in bioanalytical chemistry. In this study the relative quantities of amino acids in urine were compared between healthy control samples with those of breast cancer patients in order to determine whether there is a correlation between the levels of these biomarker compounds and breast cancer. Given a significant change in the abundance of these chemicals, they may provide modern precision medicine a new way of detecting early onset breast cancer.

Biography

Alex is a sophomore working on his Bachelor’s of Science in Chemistry. He is also involved in the Missouri S&T Student council and plans on continuing his education by attending graduate school.

Research Category

Sciences

Presentation Type

Oral Presentation

Document Type

Presentation

Award

Sciences oral presentation, Second place

Location

Carver Room

Presentation Date

11 Apr 2017, 9:40 am - 10:00 am

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Apr 11th, 9:40 AM Apr 11th, 10:00 AM

Simultaneous Determination of Amino Acids in Urine by HPLC-MS/MS for Breast Cancer Risk Screening

Carver Room

The use of biomarkers in the field of disease detection is a growing field in bioanalytical chemistry. In this study the relative quantities of amino acids in urine were compared between healthy control samples with those of breast cancer patients in order to determine whether there is a correlation between the levels of these biomarker compounds and breast cancer. Given a significant change in the abundance of these chemicals, they may provide modern precision medicine a new way of detecting early onset breast cancer.