Bifunctionalization of nanoparticles with DNA and PEG polymers
Department
Chemistry
Major
Biological Sciences
Research Advisor
Wang, Risheng
Advisor's Department
Chemistry
Funding Source
Department of Chemistry; OURE
Abstract
This research entails the findings observed while testing the binding efficiency of different ratios of bifunctionalized gold nanoparticles. A polymer, polyethylene glycol (PEG), was utilized to promote interactions between DNA origami rectangles and the gold nanoparticles. Binding yields were calculated by annealing samples with the varying ratios and analyzing them. The ratios with lower consumption of DNA provides a scaling-up potential for the application of DNA-nanoparticle conjugates in nanotechnology.
Biography
Isabella Bowling is a junior studying Biological Sciences. She is involved on campus through research under Dr. Wang, the iGEM design team, and as a Senior Resident Assistant in University Commons. After graduation, she plans to attend a graduate program for Genetic Counseling.
Research Category
Sciences
Presentation Type
Poster Presentation
Document Type
Poster
Location
Upper Atrium/Hall
Presentation Date
11 Apr 2017, 9:00 am - 11:45 am
Bifunctionalization of nanoparticles with DNA and PEG polymers
Upper Atrium/Hall
This research entails the findings observed while testing the binding efficiency of different ratios of bifunctionalized gold nanoparticles. A polymer, polyethylene glycol (PEG), was utilized to promote interactions between DNA origami rectangles and the gold nanoparticles. Binding yields were calculated by annealing samples with the varying ratios and analyzing them. The ratios with lower consumption of DNA provides a scaling-up potential for the application of DNA-nanoparticle conjugates in nanotechnology.
