Conversion of Borate Glass to Bioactive Micro-tubes
Department
Materials Science and Engineering
Major
Ceramic Engineering
Research Advisor
Rahaman, M. N., 1950-
Advisor's Department
Materials Science and Engineering
Funding Source
Center for Biomedical Science and Engineering
Abstract
Fibers of a calcium-lithium-borate glass were converted to hydroxyapatite (HA) in a KH2PO4 solution. Hollow HA micro tubes were obtained by removing the unreacted glass cores. The conversion behavior was studied with varying KH2PO4 concentrations (0.01 M, 0.02 M, and 0.10 M). For the KH2PO4 concentrations of 0.01 M and 0.02 M, glass fibers had similar conversion rates, and had a weight loss of approximately 12% and 14% respectively after 3 days. When the KH2PO4 concentration was increased to 0.10 M, glass fibers showed a much faster conversion rate and had a weight loss of approximately 60% after 3 days. The effects of heat treatments (500 °C, 700 °C, and 900 °C) on the strength of the HA tubes is currently being studied. The in vivo performance of the HA tubes is also being studied by using a rat calvarial defect model.
Biography
Nick Santoro is a senior in Ceramic Engineering and has been working as an undergraduate research assistant for Dr. Rahaman’s biomaterials group for the last year and worked for Dr. Brows’ glass research group for a year. He is a member of Keramos and Kappa Kappa Psi.
Research Category
Sciences
Presentation Type
Poster Presentation
Document Type
Poster
Location
Upper Atrium/Hall
Presentation Date
16 Apr 2014, 9:00 am - 11:45 am
Conversion of Borate Glass to Bioactive Micro-tubes
Upper Atrium/Hall
Fibers of a calcium-lithium-borate glass were converted to hydroxyapatite (HA) in a KH2PO4 solution. Hollow HA micro tubes were obtained by removing the unreacted glass cores. The conversion behavior was studied with varying KH2PO4 concentrations (0.01 M, 0.02 M, and 0.10 M). For the KH2PO4 concentrations of 0.01 M and 0.02 M, glass fibers had similar conversion rates, and had a weight loss of approximately 12% and 14% respectively after 3 days. When the KH2PO4 concentration was increased to 0.10 M, glass fibers showed a much faster conversion rate and had a weight loss of approximately 60% after 3 days. The effects of heat treatments (500 °C, 700 °C, and 900 °C) on the strength of the HA tubes is currently being studied. The in vivo performance of the HA tubes is also being studied by using a rat calvarial defect model.
