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| Title: | Photopatternable hydrogel materials for reversible optical hydrogen peroxide and glucose sensors |
| Author (s): | Pick, C. Boresi, M. Kim, C. Henthorn, David |
| Department/Lab Affiliations: | Chemical & Biological Engineering Environmental Research Center |
| Keywords: | composite hydrogel material fluorescent detection optical biosensors |
| Subject Terms: | Hydrogen peroxide. |
| Issue Date: | 2009-04 |
| Publisher: | Society of Photo-Optical Instrumentation Engineers SPIE |
| Citation: | Pick, C., M. Boresi, C. Kim, and D. Henthorn. “Photopatternable hydrogel materials for reversible optical hydrogen peroxide and glucose sensors”, Proceedings of SPIE, Vol. 7313, 73130A (2009). |
| Abstract: | In this work, a novel photopatternable hydrogel-based material for the fluorescent detection of hydrogen peroxide was developed and studied as a possible sensing element in optical biosensors. This composite hydrogel material was developed to maximize analyte transport, be amenable to existing microfabrication techniques, and dovetail with various enzyme immobilization strategies. Nanoparticles loaded with a hydrogen peroxide sensitive europium tetracycline complex (EuTc) were mixed with monomer and crosslinker to form a photopolymerizable precursor. Sensitivity to glucose can be introduced through addition of methacrylated glucose oxidase into the precursor solution, allowing for covalent immobilization of the enzyme. As a result, the material can be integrated directly into optical biosensors for continuous glucose monitoring. |
| Type: | Article - Conference proceedings text |
| In Title: | Proceedings of SPIE. |
| Copyright Notice: | This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder. No full text allowed FULL COPYRIGHT INFORMATION: |
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| title | Photopatternable hydrogel materials for reversible optical hydrogen peroxide and glucose sensors |
| contributor.author | Pick, C. |
| contributor.author | Boresi, M. |
| contributor.author | Kim, C. |
| contributor.author | Henthorn, David |
| contributor.deptlab | Chemical & Biological Engineering |
| contributor.deptlab | Environmental Research Center |
| subject | composite hydrogel material |
| subject | fluorescent detection |
| subject | optical biosensors |
| subject.LCSH | Hydrogen peroxide. |
| date.issued | 2009-04 |
| publisher | Society of Photo-Optical Instrumentation Engineers SPIE |
| identifier.citation | Pick, C., M. Boresi, C. Kim, and D. Henthorn. “Photopatternable hydrogel materials for reversible optical hydrogen peroxide and glucose sensors”, Proceedings of SPIE, Vol. 7313, 73130A (2009). |
| identifier.pub.URI | |
| description.abstract | In this work, a novel photopatternable hydrogel-based material for the fluorescent detection of hydrogen peroxide was developed and studied as a possible sensing element in optical biosensors. This composite hydrogel material was developed to maximize analyte transport, be amenable to existing microfabrication techniques, and dovetail with various enzyme immobilization strategies. Nanoparticles loaded with a hydrogen peroxide sensitive europium tetracycline complex (EuTc) were mixed with monomer and crosslinker to form a photopolymerizable precursor. Sensitivity to glucose can be introduced through addition of methacrylated glucose oxidase into the precursor solution, allowing for covalent immobilization of the enzyme. As a result, the material can be integrated directly into optical biosensors for continuous glucose monitoring. |
| type | Article - Conference proceedings |
| type.DCMIType | text |
| relation.isPartOf | Proceedings of SPIE. |
| rights | This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder. |
| rights | No full text allowed |
| rights.URI | |
| identifier.persist.URI | |
| date.available | 2009-06-19T15:38:39Z |