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| Title: | Fluidic biosensors with integrated surface bound hydrogel sensing elements |
| Author (s): | Gao, Zhan Henthorn, David Kim, Chang-Soo |
| Department/Lab Affiliations: | Biological Sciences Chemical & Biological Engineering Electrical and Computer Engineering Environmental Research Center Intelligent Microsystem Laboratory |
| Keywords: | dissolved oxygen concentration environmental areas industrial areas medical areas optical sensors |
| Issue Date: | 2009-04 |
| Publisher: | Society of Photo-Optical Instrumentation Engineers SPIE |
| Citation: | Gao, Zhan, David B. Henthorn, and Chang-Soo Kim. “Fluidic biosensors with integrated surface bound hydrogel sensing elements”, Proceedings of SPIE, Vol. 7313, 731309 (2009). |
| Abstract: | Optical sensors are a common tool to measure the dissolved oxygen concentration in environmental, industrial and medical areas. Much effort has been put on developing and using novel optical dyes and materials used as the immobilization matrixes. A poly (ethylene glycol) (PEG)-rich hydrogel was used as a fluorophore matrix. For optical sensor applications, this hydrogel was chemically anchored on negative-tone photopolymer SU-8 surface through a free radical reaction in which 1-hydroxycyclohexyl phenyl ketone (HCPK) served as the surface bound photoinitiator. Dissolved oxygen concentrations were detected based on the fluorescent intensity at emission wavelength of a fluorophore, dichlorotris (1, 10-phenanthroline) ruthenium (II) hydrate 98%, toward dissolved oxygen molecules. The normal characteristics of optical dissolved sensor were measured and recorded. All the results indicate the potential use of patternable polymerized PEGDA membranes, which is chemically anchored to SU-8 surface, as an ideal candidate matrix based on polymeric channel structures. |
| Type: | Article - Conference proceedings text |
| In Title: | Proceedings of SPIE. |
| Copyright Notice: | This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder. No full text allowed FULL COPYRIGHT INFORMATION: |
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| title | Fluidic biosensors with integrated surface bound hydrogel sensing elements |
| contributor.author | Gao, Zhan |
| contributor.author | Henthorn, David |
| contributor.author | Kim, Chang-Soo |
| contributor.deptlab | Biological Sciences |
| contributor.deptlab | Chemical & Biological Engineering |
| contributor.deptlab | Electrical and Computer Engineering |
| contributor.deptlab | Environmental Research Center |
| contributor.deptlab | Intelligent Microsystem Laboratory |
| subject | dissolved oxygen concentration |
| subject | environmental areas |
| subject | industrial areas |
| subject | medical areas |
| subject | optical sensors |
| date.issued | 2009-04 |
| publisher | Society of Photo-Optical Instrumentation Engineers SPIE |
| identifier.citation | Gao, Zhan, David B. Henthorn, and Chang-Soo Kim. “Fluidic biosensors with integrated surface bound hydrogel sensing elements”, Proceedings of SPIE, Vol. 7313, 731309 (2009). |
| identifier.pub.URI | |
| description.abstract | Optical sensors are a common tool to measure the dissolved oxygen concentration in environmental, industrial and medical areas. Much effort has been put on developing and using novel optical dyes and materials used as the immobilization matrixes. A poly (ethylene glycol) (PEG)-rich hydrogel was used as a fluorophore matrix. For optical sensor applications, this hydrogel was chemically anchored on negative-tone photopolymer SU-8 surface through a free radical reaction in which 1-hydroxycyclohexyl phenyl ketone (HCPK) served as the surface bound photoinitiator. Dissolved oxygen concentrations were detected based on the fluorescent intensity at emission wavelength of a fluorophore, dichlorotris (1, 10-phenanthroline) ruthenium (II) hydrate 98%, toward dissolved oxygen molecules. The normal characteristics of optical dissolved sensor were measured and recorded. All the results indicate the potential use of patternable polymerized PEGDA membranes, which is chemically anchored to SU-8 surface, as an ideal candidate matrix based on polymeric channel structures. |
| type | Article - Conference proceedings |
| type.DCMIType | text |
| relation.isPartOf | Proceedings of SPIE. |
| rights | This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder. |
| rights | No full text allowed |
| rights.URI | |
| identifier.persist.URI | |
| date.available | 2009-06-19T15:23:17Z |