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Title: Determining domain similarity and domain-protein similarity using functional similarity measurements of gene ontology terms
Author (s): Guntly, Lisa Michelle
Leopold, Jennifer
Maglia, Anne
Department/Lab Affiliations: Biological Sciences
Computer Science
Keywords: Gene Ontology
domain
protein
Issue Date: 2007-10
Publisher: Institute of Electrical and Electronics Engineers
Citation: "Determining Domain Similarity and Domain-Protein Similarity Using Functional Similarity Measurements of Gene Ontology Terms." Proceedings of the IEEE 7th International Symposium on Bioinformatics and Bioengineering, (2007).
Abstract: Protein domains typically correspond to major functional sites of a protein. Therefore, determining similarity between domains can aid in the comparison of protein functions, and can provide a basis for grouping domains based on function. One strategy for comparing domain similarity and domain-protein similarity is to use similarity measurements of annotation terms from the Gene Ontology (GO). In this paper five methods are analyzed in terms of their usefulness for comparing domains, and comparing domains to proteins based on GO terms.
Type: Article - Journal
text
In Title: Proceedings of the IEEE 7th International Symposium on Bioinformatics and Bioengineering
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DeterminingDomainSimilarityandDomainProteinSim_09007dcc804d6830.pdf



titleDetermining domain similarity and domain-protein similarity using functional similarity measurements of gene ontology terms
contributor.authorGuntly, Lisa Michelle
contributor.authorLeopold, Jennifer
contributor.authorMaglia, Anne
contributor.deptlabBiological Sciences
contributor.deptlabComputer Science
subjectGene Ontology
subjectdomain
subjectprotein
date.issued2007-10
publisherInstitute of Electrical and Electronics Engineers
identifier.citation"Determining Domain Similarity and Domain-Protein Similarity Using Functional Similarity Measurements of Gene Ontology Terms." Proceedings of the IEEE 7th International Symposium on Bioinformatics and Bioengineering, (2007).
identifier.pub.URI
http://www.ieeexplore.ieee.org/iel5/4375520/4375521/04375717.pdf?tp=&isnumber=4375521&arnumber=4375717
description.abstractProtein domains typically correspond to major functional sites of a protein. Therefore, determining similarity between domains can aid in the comparison of protein functions, and can provide a basis for grouping domains based on function. One strategy for comparing domain similarity and domain-protein similarity is to use similarity measurements of annotation terms from the Gene Ontology (GO). In this paper five methods are analyzed in terms of their usefulness for comparing domains, and comparing domains to proteins based on GO terms.
typeArticle - Journal
type.DCMITypetext
type.statusFinal version
rightsThis material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder.
rights.URI
http://www.ieee.org/web/publications/rights/policies.html
relation.isPartOfProceedings of the IEEE 7th International Symposium on Bioinformatics and Bioengineering
date.accessioned2008-04-08T18:57:56Z
date.available2008-04-08T18:57:58Z
identifier.persist.URI
http://scholarsmine.mst.edu/post_prints/DeterminingDomainSimilarityandDomainProteinSim_09007dcc804d67cc.html
Full Text
DeterminingDomainSimilarityandDomainProteinSim_09007dcc804d6830.pdf