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Title: Accuracy and interferences for enzyme-linked Immunoassay tests for Atrazine
Author (s): Adams, Craig D.
Jiang, H.
McGuire, M.
Graziano, N.
Roberson, A .
Frey, M.
Department/Lab Affiliations: Civil, Architectural & Environmental Engineering
Environmental Research Center
Keywords: Accuracy
Enzyme-linked
Immunoassay Test
Subject Terms: Atrazine
Issue Date: 2004
Publisher: American Water Works Association
Citation: Adams, C., Jiang, H., Graziano, N., Roberson, A., McGuire, M.,Frey, M. (2004) “Accuracy and Interferences for Enzyme-Linked Immunoassay Tests for Atrazine,” J. American Water Works Association, 96:12, 126-139.
Abstract: Atrazine is one of the most commonly used herbicides in the United States, therefore it is a regulatory concern and is extensively monitored in the environment, especially in drinking water. Because of the higher costs of gas chromatography (GC) methods, utility managers and regulators are considering the increased use of enzyme-linked immunosorbent assay (ELISA) methods for monitoring atrazine. An ELISA test kit was recently approved by the US Environmental Protection Agency. The research in this article points out potential biases and inaccuracies that may occur with such test kits. ELISA test kits for atrazine are typically precise (repeatable) but often have a tendency for a positive bias from unknown interferences. Negative biases are also observed in some cases, which suggest a lower atrazine concentration than is actually present. The results of this research can help utilities and regulators to better determine the best use of ELISA versus GC methods for analyzing atrazine with respect to monitoring and/or process control.
Type: Article - Journal
text
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http://www.awwa.org/content.cfm?ItemNumber=1649
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http://www.awwa.org/awwa/waterlibrary/scholarabstract.aspx?an=JAW_0060866
Link to this page:
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titleAccuracy and interferences for enzyme-linked Immunoassay tests for Atrazine
contributor.authorAdams, Craig D.
contributor.authorJiang, H.
contributor.authorMcGuire, M.
contributor.authorGraziano, N.
contributor.authorRoberson, A .
contributor.authorFrey, M.
contributor.deptlabCivil, Architectural & Environmental Engineering
contributor.deptlabEnvironmental Research Center
contributor.sponsorAwwa Research Foundation
subjectAccuracy
subjectEnzyme-linked
subjectImmunoassay Test
subject.LCSHAtrazine
date.issued2004
publisherAmerican Water Works Association
identifier.citationAdams, C., Jiang, H., Graziano, N., Roberson, A., McGuire, M.,Frey, M. (2004) “Accuracy and Interferences for Enzyme-Linked Immunoassay Tests for Atrazine,” J. American Water Works Association, 96:12, 126-139.
identifier.pub.URI
http://www.awwa.org/awwa/waterlibrary/scholarabstract.aspx?an=JAW_0060866
description.abstractAtrazine is one of the most commonly used herbicides in the United States, therefore it is a regulatory concern and is extensively monitored in the environment, especially in drinking water. Because of the higher costs of gas chromatography (GC) methods, utility managers and regulators are considering the increased use of enzyme-linked immunosorbent assay (ELISA) methods for monitoring atrazine. An ELISA test kit was recently approved by the US Environmental Protection Agency. The research in this article points out potential biases and inaccuracies that may occur with such test kits. ELISA test kits for atrazine are typically precise (repeatable) but often have a tendency for a positive bias from unknown interferences. Negative biases are also observed in some cases, which suggest a lower atrazine concentration than is actually present. The results of this research can help utilities and regulators to better determine the best use of ELISA versus GC methods for analyzing atrazine with respect to monitoring and/or process control.
typeArticle - Journal
type.DCMITypetext
type.statusFinal version
rightsThis material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder.
rights.URI
http://www.awwa.org/content.cfm?ItemNumber=1649
date.accessioned2007-04-11T17:00:48Z
date.available2007-12-12T23:25:29Z
identifier.persist.URI
http://scholarsmine.mst.edu/post_prints/AccuracyAndInterferencesForEnzyme-linked_09007dcc8041b860.html