We have investigated a combined 2D/3D protocol for minimizing contamination in dual tracer P.E.T. studies in which the tracers are administered on a timescale that is short compared to the half-lives. We have performed a series of phantom studies on an Advance and a Discovery ST (GE Healthcare Technologies), using a torso phantom with cardiac insert (Data Spectrum Corporation) to simulate a combined FDG and NH3 scan protocol for a patient with ischemia. The phantom was imaged in a series of alternating 2D/3D acquisitions as it decayed over 6 half-lives. By comparing 2D and 3D images, we have verified that 3D images are of comparable accuracy to 2D images, even with realistic out-of-field activity challenging the 3D scans. Based on scan and image statistical quality, we have recommended optimal doses for maximizing the image quality of both scans.
J. W. Wilson et al., "Optimizing Sequential Dual Tracer P.E.T. Studies Using a Combined 2D/3D Imaging Protocol," Nuclear Science Symposium Conference Record, 2004 IEEE, Institute of Electrical and Electronics Engineers (IEEE), Jan 2004.
The definitive version is available at http://dx.doi.org/10.1109/NSSMIC.2004.1466452
Mining and Nuclear Engineering
Keywords and Phrases
2D-3D Imaging Protocol; 3D Images; FDG; NH3; NH3 Scan Protocol; PET; Ammonia; Cardiac Insert; Cardiology; Data Spectrum Corporation; Diseases; Image Quality; Image Statistical Quality; Ischemia; Optimal Dose; Organic Compounds; Phantom Study; Phantoms; Positron Emission Tomography; Realistic Out-Of-Field Activity; Sequential Dual Tracer; Torso Phantom; Tracers
International Standard Serial Number (ISSN)
Article - Conference proceedings
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