Title

Sodium Silicate Bonded Borate Glass Scaffolds for Tissue Engineering

Abstract

Borate and silicate glass particles and microspheres with size distributions in the range of approximately 100-400 micron were loosely compacted and bonded by sodium silicate solution to prepare resorbable, porous glass constructs with porosity 30-50%. Conversion of the binding borate glass to hydroxyapatite was investigated by measuring the weight loss of the constructs in a solution of 0.25 M K2HPO4 with a pH value of 9.0 at 37 °C, as a function of time. Almost full conversion of the borate glass to hydroxyapatite was achieved in less than 6 days. X-ray diffraction revealed an initially amorphous product that subsequently crystallized to hydroxyapatite.

Department(s)

Materials Science and Engineering

Keywords and Phrases

Mechanics; Crystallography; Continuum Mechanics and Mechanics of Materials; Polymer Sciences; Characterization and Evaluation of Materials; Materials Science

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2007 Springer Verlag, All rights reserved.


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