A method is provided for preparing shells, concentric shells or porous, homogenous gels from alkali borate glass particles at low temperatures (i.e. room temperature or less than above 100° C.). The alkali borate glass particles contain one or more cations such as aluminum which react with an aqueous solution containing an anion such as hydroxide to form an aqueous insoluble material having a solubility limit of less than about 0.01 wt. percent. TTie resulting shells or gels may be used in many different applications such as a filler in resins, as filters, precursors for nano-sized powders, as thin surface films or catalyst support media. The resulting shells or gels may also have a chemotherapeutic drug added thereto, following which the resulting product is administered to a mammal and the insoluble material is dissolved form the product in vivo through administration of chelating agent.
D. E. Day and S. D. Conzone, "Method for Preparing Porous Shells or Gels from Glass Particles," The Curators of the University of Missouri, Mar 2002.
Materials Science and Engineering
Patent Application Number
US 6,358,531 B1
© 2002 The Curators of the University of Missouri, All rights reserved.