Preparation of Bioactive Glasses with Controllable Degradation Behavior and Their Bioactive Characterization
Bioactive glasses and ceramics have been widely investigated for bone repair because of their excel-lent bioactive characteristics. However, these biomaterials undergo incomplete conversion into a bone-like material, which severely limits their biomedical application. In this paper, borosilicate bioac-tive glasses were prepared by traditional melting process. The results showed that borosilicate glasses possessed high biocompatibility and bioactivity. In addition, when immersed in a 0.02 mol/L K2HPO4 solution, particles of a borate glass were fully converted to HA. The desirable conversion rate to HA may be achieved through the adjustment of the B2O3/SiO2 ratio. The results of XRD and FTIR analysis indicated that the degradation product was carbonate-substituted hydroxyapatite, which was similar to the inorganic component of bone.
A. Yao et al., "Preparation of Bioactive Glasses with Controllable Degradation Behavior and Their Bioactive Characterization," Chinese Science Bulletin, Springer Verlag, Jan 2007.
The definitive version is available at http://dx.doi.org/10.1007/s11434-007-0023-5
Materials Science and Engineering
Shanghai Key Fundamental Research Project
University of Missouri--Rolla
Keywords and Phrases
Bioactive Glass; Bioactivity; Borosilicate Glass; Biodegradation
Article - Journal
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