Title

Preparation of Bioactive Glasses with Controllable Degradation Behavior and Their Bioactive Characterization

Abstract

Bioactive glasses and ceramics have been widely investigated for bone repair because of their excel-lent bioactive characteristics. However, these biomaterials undergo incomplete conversion into a bone-like material, which severely limits their biomedical application. In this paper, borosilicate bioac-tive glasses were prepared by traditional melting process. The results showed that borosilicate glasses possessed high biocompatibility and bioactivity. In addition, when immersed in a 0.02 mol/L K2HPO4 solution, particles of a borate glass were fully converted to HA. The desirable conversion rate to HA may be achieved through the adjustment of the B2O3/SiO2 ratio. The results of XRD and FTIR analysis indicated that the degradation product was carbonate-substituted hydroxyapatite, which was similar to the inorganic component of bone.

Department(s)

Materials Science and Engineering

Sponsor(s)

Shanghai Key Fundamental Research Project
University of Missouri--Rolla

Keywords and Phrases

Bioactive Glass; Bioactivity; Borosilicate Glass

Library of Congress Subject Headings

Biodegradation

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2007 Springer Verlag, All rights reserved.

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