Masters Theses
Title
N-Acetylcystein amide protects against methamphetamine-induced oxidative stress in human brain endothelial cells
Abstract
"Oxidative stress plays an important role in neurodegenerative disorders such as Parkinson's disease and Alzheimer's disease. Methamphetamine (METH) is an amphetamine analog that causes degeneration of the dopaminergic system in mammals and subsequent oxidative stress. In our present study, we have used immortalized human brain microvascular endothelial cells to test whether METH induces oxidative stress in vitro and the ability of a new antioxidant, N-Acetylcystein amide (NACA), to prevent METH-induced oxidative stress"--Abstract, leaf iii.
Advisor(s)
Ercal, Nuran
Committee Member(s)
Ma, Yinfa
Huang, Yue-wern
Department(s)
Chemistry
Degree Name
M.S. in Chemistry
Publisher
Missouri University of Science and Technology
Publication Date
Fall 2008
Pagination
ix, 52 leaves
Note about bibliography
Includes bibliographical references (leaves 151-153).
Rights
© 2008 Xinsheng Zhang, All rights reserved.
Document Type
Thesis - Citation
File Type
text
Language
English
Library of Congress Subject Headings
Methamphetamine -- Physiological effect
Nervous system -- Degeneration -- Pathophysiology
Oxidative stress
Thesis Number
T 9451
Print OCLC #
316196920
Link to Catalog Record
Full-text not available: Request this publication directly from Missouri S&T Library or contact your local library.
http://laurel.lso.missouri.edu/record=b6665295~S5Recommended Citation
Zhang, Xinsheng, "N-Acetylcystein amide protects against methamphetamine-induced oxidative stress in human brain endothelial cells" (2008). Masters Theses. 81.
http://scholarsmine.mst.edu/masters_theses/81