Keywords and Phrases
13-93 Bioactive glass; Extrusion fabrication; Scaffolds
"Although implants made with bioactive glass have shown promising results for bone repair, their application in repairing load-bearing long bones is limited due to their poor mechanical properties as compared to human bones. This thesis study is on freeform extrusion fabrication of silicate based 13-93 bioactive glass scaffolds reinforced with titanium fibers. A composite paste was prepared with 13-93 bioactive glass filled with titanium fibers (~16 µm in diameter and aspect ratio of ~250) having 0.1 to 0.4 vol. % of the bioactive glass scaffold. This paste was then filled into a syringe manually, and then extruded through a nozzle to fabricate scaffolds with an extrudate diameter of about ~0.8 mm. The sintered scaffolds, with and without titanium fibers, had measured pore sizes ranging from 400 to 800 µm and a porosity of ~50%. Scaffolds produced with 0.4 vol. % titanium fibers were measured to have a fracture toughness of ~0.8 MPa·m1/2 and a flexural strength of ~15 MPa. Bioactive glass scaffolds without titanium fibers had a toughness of ~0.5 MPa·m1/2 and strength of ~10 MPa. The addition of titanium fibers increased the fracture toughness of the scaffolds by ~70% and flexural strength by ~40%. The scaffolds' biocompatibility and their degradation in mechanical properties in vitro were assessed by immersing the scaffolds in a simulated body fluid over a period of one to four weeks"--Abstract, page iii.
Leu, M. C. (Ming-Chuan)
Mechanical and Aerospace Engineering
M.S. in Mechanical Engineering
Missouri University of Science and Technology
viii, 40 pages
© 2015 Albin Thomas, All rights reserved.
Thesis - Open Access
Library of Congress Subject Headings
Glass in medicine
Solid freeform fabrication
Electronic OCLC #
Thomas, Albin, "Freeform extrusion fabrication of titanium fiber reinforced 13-93 bioactive glass scaffolds" (2015). Masters Theses. 7483.