Masters Theses

Title

Enzymatic synthesis and characterization of acidic amino acid oligomers

Author

Hao Wang

Abstract

"Glutamic acid (Glu) and aspartic acid (Asp) are dicarboxylic amino acids and are negatively charged at physiological pH. Glutamate is a key molecule in cellular metabolism and serves as metabolic fuel in the body. It is also the most abundant excitatory neurotransmitter in the mammalian nervous system and it is believed to be involved in cognitive functions such as learning and memory retention...The present study was designed to investigate an enzymatic route for synthesis of aspartate and glutamate homo-oligopeptides. Synthesis route involved the use of a readily available proteolytic enzyme papain that has been used for synthesis of non-polar and basic amino acid peptides"--Abstract, leaf iii.

Advisor(s)

Kapila, Shubhender

Committee Member(s)

Nam, Paul Ki-souk
Westenberg, David J.

Department(s)

Chemistry

Degree Name

M.S. in Chemistry

Publisher

University of Missouri--Rolla

Publication Date

Fall 2006

Pagination

xi, 54 leaves

Note about bibliography

Includes bibliographical references (pages 50-51).

Rights

© 2006 Hao Wang, All rights reserved.

Document Type

Thesis - Citation

File Type

text

Language

English

Library of Congress Subject Headings

Amino acids -- Metabolism
Aspartic acid
Glutamic acid
High performance liquid chromatography
Oligomers
Papain

Thesis Number

T 9094

Print OCLC #

124045397

Link to Catalog Record

Full-text not available: Request this publication directly from Missouri S&T Library or contact your local library.

http://laurel.lso.missouri.edu/record=b5849637~S5

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