Keywords and Phrases
ESTminer; Negative selection pattern (NSP)
"Current gene identification (GI) techniques typically rely on matching biological or chemical properties of specific genes, specific species, specific ecotypes, etc...In this thesis, a new automated GI technique is proposed, and compared against another computer-based technique proposed earlier. Both methods utilize EST data available from NCBI databases to discover previously unknown genes. The newly proposed method identifies one gene family at a time and is based on a distinctive negative selection pattern (NSP) of differences, which is seen between the coding regions of gene family members. The other technique, called ESTminer, attempts genome-wide gene family identification for any organism, by detecting single nucleotide polymorphisms between potential family members. In this thesis, a complete automated analysis of both techniques is presented"--Abstract, page iii.
Frank, Ronald L.
M.S. in Computer Science
University of Missouri--Rolla
vii, 37 pages
© 2007 Cyriac Kandoth, All rights reserved.
Thesis - Open Access
Library of Congress Subject Headings
Genes -- Identification
Print OCLC #
Electronic OCLC #
Link to Catalog Recordhttp://laurel.lso.missouri.edu/record=b6430492~S5
Kandoth, Cyriac, "A quantitative study of gene identification techniques based on evolutionary rationales" (2007). Masters Theses. 4586.