Masters Theses
Title
Influence of S-nitrosylation on muscarinic acetylcholine receptors
Keywords and Phrases
Methylscopolamine
Abstract
"Muscarinic acetylcholine receptors possess a conserved pair of extracellular cysteines which form a disulfide bond between the 1st and the 2nd extracellular loop. Previous work has shown that the disulfide bond forming cysteines influence ligand binding and receptor interaction with transducer proteins. Nitric oxide (NO) has multiple roles in cellular signaling. One mechanism for NO activity is the nitrosylation of protein sulfhydryl groups. Accordingly, in the present studies the role of the nitric oxide generating compound sodium nitroprusside on ligand binding to muscarinic receptors of rat brainstem was studied"--Abstract, leaf iii.
Advisor(s)
Aronstam, Robert
Committee Member(s)
Shannon, Katie
Ercal, Nuran
Department(s)
Biological Sciences
Degree Name
M.S. in Applied and Environmental Biology
Publisher
University of Missouri--Rolla
Publication Date
Spring 2007
Pagination
x, 57 leaves
Note about bibliography
Includes bibliographical references.
Rights
© 2007 Pradnya Pandurang Patil, All rights reserved.
Document Type
Thesis - Citation
File Type
text
Language
English
Library of Congress Subject Headings
Cellular signal transduction
G proteins
Muscarinic receptors
Thesis Number
T 9130
Print OCLC #
173309875
Link to Catalog Record
Full-text not available: Request this publication directly from Missouri S&T Library or contact your local library.
http://laurel.lso.missouri.edu/record=b5973583~S5Recommended Citation
Patil, Pradnya Pandurang, "Influence of S-nitrosylation on muscarinic acetylcholine receptors" (2007). Masters Theses. 26.
http://scholarsmine.mst.edu/masters_theses/26
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