Abstract

We propose a novel method to overcome significant problems of baseline drift and sensitivity degradation in amperometric biosensors based on oxidase enzyme reactions. A novel glucose microsensor with a built-in electrochemical oxygen manipulation microsystem is introduced to demonstrate three novel functionalities; one-point in situ self-calibration (zero-point), broadening of dynamic range and increase in sensitivity. The influence of electrochemically generated oxygen microenvironment on the sensor output within a fluidic structure is investigated.

Meeting Name

3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology, 2005

Department(s)

Electrical and Computer Engineering

Second Department

Chemical and Biochemical Engineering

Sponsor(s)

National Science Foundation (U.S.)

Library of Congress Subject Headings

Electrolysis
Hydrogen
Oxygen

Document Type

Article - Conference proceedings

Document Version

Final Version

File Type

text

Language(s)

English

Rights

© 2005 Institute of Electrical and Electronics Engineers (IEEE), All rights reserved.

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