Biochemical sensors for continuous monitoring require dependable periodic self diagnosis with acceptable simplicity to check its functionality during operation. An in-situ self-diagnostic technique for a dissolved oxygen microsensor is proposed in an effort to devise an intelligent microsensor system with an integrated electrochemical actuation electrode. With a built-in platinum microelectrode that surrounds the microsensor, two kinds of microenvironments, called the oxygen-saturated or oxygen-depleted phases, can be created by water electrolysis, depending on the polarity. The functionality of the microsensor can be checked during these microenvironment phases. The polarographic oxygen microsensor is fabricated on a flexible polyimide substrate (Kapton) and the feasibility of the proposed concept is demonstrated in a physiological solution. The sensor responds properly during the oxygen-generating and oxygen-depleting phases. The use of these microenvironments for in-situ self-calibration is discussed to achieve functional integration, as well as structural integration, of the microsensor system.
C. Kim et al., "Manipulation of Microenvironment with a Built-in Electrochemical Actuator in Proximity of a Dissolved Oxygen Microsensor," IEEE Sensors Journal, Institute of Electrical and Electronics Engineers (IEEE), Jan 2004.
The definitive version is available at http://dx.doi.org/10.1109/JSEN.2004.832857
Electrical and Computer Engineering
Chemical and Biochemical Engineering
Keywords and Phrases
Electrolysis; Biochemical Sensors; Biosensors; Dissolved Oxygen Microsensor; Electrochemical Actuator; Electrochemical Electrodes; Electrochemical Sensors; Electrolysis; In-Situ Self-Calibration; Intelligent Microsensor; Intelligent Sensors; Microenvironment Manipulation; Microsensors; Oxygen; Oxygen-Depleted Phase; Oxygen-Saturated Phase; Periodic Self Diagnosis; Polarographic Oxygen Microsensor; Polyimide; Polyimide Substrate; Self Calibration; Self Diagnosis; Water Electrolysis
International Standard Serial Number (ISSN)
Article - Journal
© 2004 Institute of Electrical and Electronics Engineers (IEEE), All rights reserved.