Abstract

Recent developments for biosensors have been mainly focused on miniaturization and exploratory use of new materials. It should be emphasized that the absence of a novel "in-situ self-calibration/diagnosis technique" that is not connected to an external apparatus is a key obstacle to the realization of a biosensor for continuous use with minimum attendance. To address this deficiency, a novel needle-type biosensor system with fully automated operations is being developed, in which a novel oxidase-coupled amperometric sensor with oxygen depleting/generating actuator is interfaced with an electrochemical instrument and a perfusion system. Labview virtual instrument has been also developed to oversee the automatic control of the prototype sensor. Using the proposed system, a large amount of data can be rapidly collected for more effective sensor characterization and more advanced sensor designs. Autonomous and continuous sensing and self-calibration with minimal human intervention is also envisioned.

Meeting Name

2006 IEEE Instrumentation and Measurement Technology

Department(s)

Electrical and Computer Engineering

Second Department

Chemical and Biochemical Engineering

Keywords and Phrases

Actuator; Automation; Calibration; Continuous Calibration/Sensing; GOD (Glucose Oxidase); LOD (Lactate Oxidase); LabView; Needle Based Amperometric Sensor; Solid-State Biosensor; Water Electrolysis

International Standard Serial Number (ISSN)

1091-5281

Document Type

Article - Conference proceedings

Document Version

Final Version

File Type

text

Language(s)

English

Rights

© 2006 Institute of Electrical and Electronics Engineers (IEEE), All rights reserved.

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