Recent developments for biosensors have been mainly focused on miniaturization and exploratory use of new materials. It should be emphasized that the absence of a novel "in-situ self-calibration/diagnosis technique" that is not connected to an external apparatus is a key obstacle to the realization of a biosensor for continuous use with minimum attendance. To address this deficiency, a novel needle-type biosensor system with fully automated operations is being developed, in which a novel oxidase-coupled amperometric sensor with oxygen depleting/generating actuator is interfaced with an electrochemical instrument and a perfusion system. Labview virtual instrument has been also developed to oversee the automatic control of the prototype sensor. Using the proposed system, a large amount of data can be rapidly collected for more effective sensor characterization and more advanced sensor designs. Autonomous and continuous sensing and self-calibration with minimal human intervention is also envisioned.
Y. Yellambalase et al., "Automated Oxidase-Coupled Amperometric Microsensor with Integrated Electrochemical Actuation System for Continuous Sensing of Saccharoids," Proceedings of the 2006 IEEE Instrumentation and Measurement Technology, Institute of Electrical and Electronics Engineers (IEEE), Jan 2006.
The definitive version is available at http://dx.doi.org/10.1109/IMTC.2006.328252
2006 IEEE Instrumentation and Measurement Technology
Electrical and Computer Engineering
Chemical and Biochemical Engineering
Keywords and Phrases
Actuator; Automation; Calibration; Continuous Calibration/Sensing; GOD (Glucose Oxidase); LOD (Lactate Oxidase); LabView; Needle Based Amperometric Sensor; Solid-State Biosensor; Water Electrolysis
International Standard Serial Number (ISSN)
Article - Conference proceedings
© 2006 Institute of Electrical and Electronics Engineers (IEEE), All rights reserved.