A study of the beneficial role of thiol antioxidant supplementation in various forms of glutathione deficiency
"Oxidative stress plays a major role in the pathology of numerous disorders afflicting humans, ranging from neurodegenerative diseases, to cancer, and heavy metal toxicity. Scientists are on the constant lookout for new and better antioxidants that have the ability to slow, if not stop the harmful degenerative effects of free radicals in oxidative stress related disorders. Both synthetic and naturally occurring compounds are being constantly screened for their antioxidant properties. This study attempted to evaluate the abilities of a thiol antioxidant, N-Acetylcysteine amide (NACA), to protect cells from the harmful effects of gluthathione depletion in two different models of oxidative stress"--Abstract, leaf iii.
Lutz, Paula Marcellus, 1954-
Ph. D. in Chemistry
National Institutes of Health (U.S.)
Missouri University of Science and Technology
Journal article titles appearing in thesis/dissertation
- Tert-butyl hydroperoxide induced oxidative damage in ARPE-19 cells and protection by N-Acetylcysteine amide
- Antioxidant status of cultured fibroblasts from patients with glutathione synthetase deficiency and benefits of thiol supplementation
- Characterization of antioxidant status of mice heterozygous for glutathione synthetase
xiii, 115 leaves
© 2009 Linu Sara Abraham, All rights reserved.
Dissertation - Citation
Library of Congress Subject Headings
Antioxidants -- Therapeutic use
Print OCLC #
Link to Catalog Record
Full-text not available: Request this publication directly from Missouri S&T Library or contact your local library.http://laurel.lso.missouri.edu/record=b7429843~S5
Abraham, Linu Sara, "A study of the beneficial role of thiol antioxidant supplementation in various forms of glutathione deficiency" (2009). Doctoral Dissertations. 1775.