Doctoral Dissertations

Title

Part I. Enantioenrichment of α-hydroxy acids through lipase catalyzed esterification; Part II. Synthesis, purification and characterization of novel molecule, sulfonium (3-hydroxy-3-carboxypropyl)-dimethyl chloride; Part III. Synthesis, purification and characterization of potential cancer chemopreventive compound,2-hydroxy-4-(methyl seleno)-butanioc acid

Alternative Title

Enantioenrichment of [alpha]-hydroxy acids through lipase catalyzed esterification
Synthesis, purification and characterization of novel molecule, sulfonium (3-hydroxy-3-carboxypropyl)-dimethyl chloride
Synthesis, purification and characterization of potential cancer chemopreventive compound,2-hydroxy-4-(methyl seleno)-butanioc acid

Author

Shiva Garg

Keywords and Phrases

Novel molecules

Abstract

"This dissertation is divided into three sections that cover three separate but related topics. The first section deals with a preparative scale separation of 2-Hydroxy-4-(methyl thio)-butanoic acid (HMTBA), the hydroxy analog of limiting amino acid Methionine (Met.)...The second section of the dissertation deals with the synthesis of S-methyl HMTBA, an analog of S-methyl methionine (SMM); Vitamin U...The research described in the third section was directed at the synthesis of a selenium analog of HMTBA (Se-HMTBA)--Abstract, leaf iii.

Advisor(s)

Kapila, Shubhender

Committee Member(s)

Ma, Yinfa
Ercal, Nuran
Nam, Paul Ki-souk
Forciniti, Daniel

Department(s)

Chemistry

Degree Name

Ph. D. in Chemistry

Sponsor(s)

Novus (Firm)

Publisher

University of Missouri--Rolla

Publication Date

Fall 2007

Pagination

xvi, 171 leaves

Note about bibliography

Includes bibliographical references (leaves 160-170).

Rights

© 2007 Shiva Garg, All rights reserved.

Document Type

Dissertation - Citation

File Type

text

Language

English

Library of Congress Subject Headings

Cancer -- Chemoprevention
Hydroxy acids
Lipase
Selenium compounds
Sulfur compounds

Thesis Number

T 9390

Print OCLC #

261216693

Link to Catalog Record

Full-text not available: Request this publication directly from Missouri S&T Library or contact your local library.

http://laurel.lso.missouri.edu/record=b6490329~S5

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