Doctoral Dissertations
Synthesis, structural characterization and biological properties of ortho-quinone derivatives and their metal conjugates
Abstract
"The synthesis and characterization of the Phenanthrenequinone Semicarbazone, 4-phenylsemicarbazone and Benzoic Hydrazone with 1,2-naphthoquinone-monoxime are reported. The X-ray crystal structure of the Phenanthrenequinone Semicarbazone (PQSC), 4-phenylsemicarbazone (PQPSC) and Benzoic Hydrazone (PQBH) confirms the presence of the E tautomeric arrangement in these compounds. The free 1,2-naphthoquinone-monoximes exist in the quinonemonoxime form. The X-ray crystal structure of the complexes, viz. [Ni(PQSC)₂], [Zn(PQSC)₂], reveals that the SC ligands behave as a tridentate monoanionic ligand coordinating through quinone oxygen, enolate oxygen, and azomethine nitrogen forming a distorted octahedron with the metal ion at the center. The nickel, cobalt and zinc complexes show 1:2 stoichiometry while copper complex shows 1:1 metal to ligand ratio in all the synthesized metal complexes"--Abstract, page iii.
Advisor(s)
Sinn, Ekkehard
Committee Member(s)
Collier, Harvest L.
Reddy, Prakash
Aronstam, Robert
Switzer, Jay A., 1950-
Department(s)
Chemistry
Degree Name
Ph. D. in Chemistry
Publisher
University of Missouri--Rolla
Publication Date
Fall 2006
Pagination
xiii, 140 pages
Note about bibliography
Includes bibliographical references (pages 134-139).
Rights
© 2006 Di Xiao, All rights reserved.
Document Type
Dissertation - Citation
File Type
text
Language
English
Subject Headings
Antineoplastic agents
Crystals -- Structure
Metal complexes
Quinone
Thesis Number
T 9054
Print OCLC #
173175743
Link to Catalog Record
Full-text not available: Request this publication directly from Missouri S&T Library or contact your local library.
http://merlin.lib.umsystem.edu/record=b5962535~S5Recommended Citation
Xiao, Di, "Synthesis, structural characterization and biological properties of ortho-quinone derivatives and their metal conjugates" (2006). Doctoral Dissertations. 1713.
https://scholarsmine.mst.edu/doctoral_dissertations/1713
Share My Dissertation If you are the author of this work and would like to grant permission to make it openly accessible to all, please click the button above.
