Nanoscale Sensor Design via in Situ Labeling of Gold Nanoparticles onto Protein Scaffolds
A one-step method for synthesis of bioconjugated gold nanoparticles is reported. A non-toxic and biocompatible phosphorus based reducing agent was used for reduction of gold (III) and formation of nanoparticles. Physicochemical properties of protein-A stabilized gold nanoparticls were investigated. Result of immunoassay experiments confirmed the potential of the synthesized anti-protein-A conjugated gold nanoparticles for use as a simple and inexpensive test for quantitative screening of protein-A samples.
Z. Afrasiabi Navan et al., "Nanoscale Sensor Design via in Situ Labeling of Gold Nanoparticles onto Protein Scaffolds," Journal of Nanoscience and Nanotechnology, vol. 10, no. 2, pp. 719-725, American Scientific Publishers, Feb 2010.
The definitive version is available at http://dx.doi.org/10.1166/jnn.2010.1906
Keywords and Phrases
Gold Nanoparticles; In-situ; Nanoscale sensors; One-step methods; Physicochemical property; Quantitative screening; Antibodies; Gold; Gold compounds; Phosphorus; Sensors; Antibody; Nanoparticles; Protein a.; SensorNanoparticles; gold; metal nanoparticle; protein, article; chemistry; nanotechnology; Gold; Metal Nanoparticles; Nanotechnology; Proteins
International Standard Serial Number (ISSN)
Article - Journal
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