D-amino Acid Levels in Human Physiological Fluids
Plasma, urine, cerebrospinal fluid (CSF), and amniotic fluid were examined to determine whether free D-amino acids were present and if so at what levels. It was found that D-amino acids exist in all physiological fluids tested, but that their level varied, considerably. the lowest levels of D-amino acids were usually found in amniotic fluid or CSF (almost always 90%). Correspondingly high levels of D-pipecolic acid were not found in plasma. Some of the trends found in this work seemed to be analogous to those found in a recent rodent study.
N. Ercal et al., "D-amino Acid Levels in Human Physiological Fluids," Chirality, Wiley-Blackwell, Jan 1993.
The definitive version is available at http://dx.doi.org/10.1002/chir.530050519
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© 1993 Wiley-Blackwell, All rights reserved.