Antioxidant Therapy in Alzheimer's Disease: Theory and Practice
Alzheimer disease treatment has yet to yield a successful therapy that addresses the source of the damage found in brains. Of the varied proposed theories of AD etiology, reactive oxygen species (ROS) generation is cited as a common factor. Efforts to reduce the pathology associated with ROS via antioxidants therefore offer new hope to patients suffering from this devastative disease.
G. Aliev et al., "Antioxidant Therapy in Alzheimer's Disease: Theory and Practice," Mini Reviews in Medicinal Chemistry, vol. 8, no. 13, pp. 1395-1406, Bentham Science Publishers, Nov 2008.
The definitive version is available at http://dx.doi.org/10.2174/138955708786369582
Keywords and Phrases
antioxidant; scavenger; Alzheimer disease; animal; brain; drug effect; genetics; human; metabolism; oxidative stress; pathology; Free Radical Scavengers
International Standard Serial Number (ISSN)
Article - Journal
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