Title

Metal-Ion Responsive Reversible Assembly of DNA Origami Dimers: G-Quadruplex Induced Intermolecular Interaction

Abstract

We present a novel metal-ion stimulated organization of DNA origami nanostructures by employing G-quadruplexes as stimuli-responsive bridges. The reversible assembly process of DNA origami was the result of conformational changes between the G-quadruplex and its single-strand state induced by monovalent cations. This study might stimulate a new design of responsive DNA-based intelligent nanomaterials.

Department(s)

Chemistry

Comments

This work is supported by University of Missouri Research Board, Material Research Center at Missouri University of Science and Technology and College of arts and Science of Missouri S&T.

Keywords and Phrases

Assembly process; Conformational change; DNA origamis; G-quadruplexes; Intermolecular interactions; Monovalent cations; Stimuli-responsiv

International Standard Serial Number (ISSN)

2040-3364

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2018 Royal Society of Chemistry, All rights reserved.

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