Abstract

Recently, Levitt and co-workers demonstrated that conserving the population of long-lasting nuclear singlet states in weak magnetic fields can lead to a preservation of nuclear spin information over times substantially longer than governed by the (high-field) spin-lattice relaxation time T1. Potential benefits of the prolonged spin information for magnetic resonance imaging and spectroscopy were pointed out, particularly when combined with the parahydrogen induced polarization (PHIP) methodology. In this contribution, we demonstrate that an increase of the effective relaxation time by a factor up to three is achieved experimentally, when molecules hyperpolarized by PHIP are kept in a weak magnetic field instead of the strong field of a typical NMR magnet. This increased lifetime of spin information makes the known PHIP phenomena more compatible with the time scales of biological processes and, thus, more attractive for future investigations.

Department(s)

Chemistry

Sponsor(s)

Center of Advanced Imaging (University of Magdeburg)
German Research Association

Keywords and Phrases

Nuclear Spin-Lattice Relaxation; Polarisation

Library of Congress Subject Headings

Nuclear magnetic resonance
Proton magnetic resonance

International Standard Serial Number (ISSN)

00219606

Document Type

Article - Journal

Document Version

Final Version

File Type

text

Language(s)

English

Rights

© 2006 American Institute of Physics (AIP), All rights reserved.

Full Text Link

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Chemistry Commons

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