Assembly of Heterogeneous Functional Nanomaterials on DNA Origami Scaffolds
One on each side: Gold nanoparticles (AuNPs) and semiconducting quantum dots (QDs) are integrated on a single DNA origami scaffold. Streptavidin- functionalized QDs bind to biotin anchors on one side of the DNA origami, while DNA-coated AuNPs bind through DNA hybridization to single-stranded DNA on the other side of the scaffold. This approach offers a new path toward the organization of complex systems consisting of disparate materials.
R. Wang et al., "Assembly of Heterogeneous Functional Nanomaterials on DNA Origami Scaffolds," Angewandte Chemie - International Edition, vol. 51, no. 45, pp. 11325-11327, Wiley, Jan 2012.
The definitive version is available at http://dx.doi.org/10.1002/anie.201206389
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