Bioactive Glasses for Nonbearing Applications in Total Joint Replacement
Bioactive ceramics, glasses, and glass-ceramics have the ability to enhance bone formation and bond to surrounding tissue. The purpose of this report is to explore the use of a silicate-based bioactive glass, designated 13-93, as an alternative for nonbearing applications in total joint replacement, such as the tibia and the meniscus. The mechanical strength of porous 13-93 glass constructs, coupled with the ability of the glass to support cell attachment, growth, and differentiation, and the fabrication of the glass into porous, three-dimensional constructs with anatomically correct shapes, indicates the potential of 13-93 glass for nonbearing applications in total joint replacement, and for bone tissue engineering applications.
M. N. Rahaman et al., "Bioactive Glasses for Nonbearing Applications in Total Joint Replacement," Seminars in Arthroplasty, vol. 17, no. 3-4, pp. 102-112, Elsevier, Sep 2006.
The definitive version is available at http://dx.doi.org/10.1053/j.sart.2006.09.003
Materials Science and Engineering
Keywords and Phrases
bioactive glass; bone repair; synthetic implant; alkaline phosphatase; aluminum oxide; hydroxyapatite; magnesium oxide; silicate; silicon dioxide
International Standard Serial Number (ISSN)
Article - Journal
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